Bioidentical hormones are non-synthetic, plant-based hormones that are identical biologically to human hormone. The best analogy to differentiate bioidentical from synthetic hormones is to look at the hormones and the receptors they activate (hundreds of thousands in our bodies) as a lock and key. The hormone is the key and the receptors they work upon are the locks. Bioidentical hormones fit perfectly in the lock, and unlock all of the beneficial effects of hormones, and when dosed properly, as with the BioTE Pellet Therapy method, have minimal to no side effects. Synthetic hormones, however, fit in the lock, but do not turn the lock and release many untoward side effects.